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What is Tacrolimus for:
This medication is an immunosupressant, prescribed for preventing organ rejection during transplantation. It decreases the activity of immune system to prevent an organ from rejection.
How does Tacrolimus work:
Tacrolimus helps the body accept an organ transplant. It lowers the bodys harmful response to diseases of the immune system.
How should Tacrolimus be used:
It comes as an ointment to apply topically as directed by your physician. Topical- As 0.03% ointment- Apply a thin layer over the affected skin twice daily.
Common side effects of Tacrolimus :
High blood pressure. Kidney function that gets worse. Chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. Headache. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Loose stools (diarrhea). Not able to sleep. Sunburn.
What do I do if I miss a dose
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.
What precautions should I take when taking Tacrolimus :
If you have an allergy to tacrolimus or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are breast-feeding.
When do I need to seek medical help
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain. Very bad headache. Any bruising or bleeding. More trips to the bathroom, more thirst, or weight loss. Not able to pass urine. Very bad swelling. Any rash. Side effect or health problem is not better or you are feeling worse.
Can I take Tacrolimus with other medicines:
Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.
Are there any food restrictions
Avoid Alcohol
How do I store Tacrolimus :
Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.
Pregnancy Category
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Therapeutic Classification
Immunosuppressants, Immunosuppressants
Country Of Origin : India
Tacrolimus is an immunosuppressant prescribed for preventing organ rejection during transplantation procedures, such as kidney, liver, or heart transplants. Available in a convenient 1.0mg dosage, tacrolimus works by decreasing the activity of the immune system, thereby helping the body accept the new organ and preventing it from rejecting the transplant.
Tacrolimus helps modulate the body's immune response to reduce the likelihood of organ rejection. After an organ transplant, the immune system typically identifies the new organ as a foreign body and attempts to attack it. Tacrolimus interferes with the proliferation and activity of T-lymphocytes (a type of white blood cell), which are primarily responsible for initiating the immune response against the transplanted organ. By lowering the activity of these cells, tacrolimus helps the body to accept the new organ.
Dosage and Administration: - Form: Capsule - Strength: 1.0mg - Route: Oral
Instructions: - Take tacrolimus exactly as prescribed by your healthcare provider. - It is typically taken once or twice daily, depending on the specific instructions given by the healthcare provider. - Swallow the capsule whole with a glass of water. - It can be taken with or without food, but it is important to be consistent in the manner you take it to maintain stable drug levels in the body. - Avoid consuming grapefruit or grapefruit juice as it can alter the drug's absorption and increase the risk of side effects.
Contact your healthcare provider or seek emergency help if you experience severe side effects such as: - Wheezing, chest tightness, fever, severe itching, bad cough, blue or gray skin color, seizures, or swelling of the face, lips, tongue, or throat. - Symptoms of infection, such as a high fever, chills, severe sore throat, sinus pain, excessive phlegm, painful urination, mouth sores, wounds that won't heal, or rectal pain. - Severe headache, uncontrollable bleeding or bruising, excessive thirst, increased urination, weight loss, inability to pass urine, or severe swelling. - Any other severe or unusual symptoms or side effects.
Always inform your healthcare provider of all medications and supplements you are taking. Tacrolimus can interact with a variety of medications, including but not limited to: - Antibiotics - Antifungal medications - Anti-seizure medications - Other immunosuppressants - Non-steroidal anti-inflammatory drugs (NSAIDs) - Cholesterol-lowering drugs - Certain herbal supplements
Taking tacrolimus with other drugs may require dosage adjustments or additional monitoring.