Testube EDTA

ethylene diamine tetra acetic - It is used in medicine to prevent blood samples from clotting and to remove calcium and lead from the body. It is also used to keep bacteria from forming a biofilm (thin layer stuck to a surface). It is a type of chelating agent. Also called eidetic acid and ethylene diamine tetra acetic acid.

Complete blood count (CBC), which includes:

White blood cell count (WBC)

Red blood cell count (RBC)

Platelet count

Hematocrit red blood cell volume (HCT)

Hemoglobin concentration (HB). This is the oxygen-carrying protein in red blood cells.

Differential white blood count

Red blood cell indices (measurements)

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Comprehensive Description of Testube EDTA

Introduction

Testube EDTA is an essential laboratory supply widely used in the field of haematology for the collection, transportation, and preservation of whole blood samples. As a critical component for carrying out various blood tests and analyses, this product ensures the integrity and reliability of the samples, thereby contributing significantly to accurate diagnostic results. This detailed product description will explore all facets of Testube EDTA, with a focus on its chemical composition, mechanisms of action, specific applications, benefits, and variants, primarily K2 EDTA and K3 EDTA.

Chemical Composition and Mechanisms

EDTA: Ethylene Diamine Tetra Acetic Acid

EDTA stands for Ethylene Diamine Tetra Acetic Acid, a potent chelating agent that binds to metal ions. The role of EDTA in Testube EDTA tubes is pivotal, particularly in inhibiting the blood coagulation process. When mixed with blood, EDTA sequesters calcium ions (Ca2+), which are crucial mediators in the coagulation cascade. By effectively removing these ions, EDTA prevents blood from clotting, thereby preserving the sample in its whole blood form for further analysis.

Variants: K2 EDTA and K3 EDTA

Testube EDTA comes in two primary variants: K2 EDTA and K3 EDTA. These variants differ in the number of chelated potassium ions, which alters their effectiveness and specific use cases.

• K2 EDTA: This form contains two chelated potassium ions. It is commonly used for standard haematological tests and is known for preserving the morphology of blood cells, making it suitable for various diagnostic purposes.

• K3 EDTA: This variant contains three chelated potassium ions. Its higher ion count potentially offers a more rapid anticoagulation process. However, it might alter cell morphology slightly more than K2 EDTA, which could influence the results in certain analyses.

Applications in Haematology

One of the most significant uses of Testube EDTA is in conducting a Complete Blood Count (CBC), which is a crucial diagnostic test that evaluates the overall health and detects a variety of disorders, including anemia, infection, and many other diseases. The CBC includes several measurements:

• White Blood Cell Count (WBC): Measures the number of white blood cells, which are crucial for fighting infection.

• Red Blood Cell Count (RBC): Determines the number of red blood cells that carry oxygen from the lungs to the rest of the body.

• Platelet Count: Evaluates the number of platelets, which are essential for blood clotting.

• Hematocrit (HCT): Measures the proportion of blood volume that is occupied by red blood cells.

• Hemoglobin Concentration (HB): Determines the amount of the oxygen-carrying protein in the blood.

• Differential White Blood Count: Provides the percentages of different types of white blood cells.

• Red Blood Cell Indices: These measurements include MCV (Mean Corpuscular Volume), MCH (Mean Corpuscular Hemoglobin), and MCHC (Mean Corpuscular Hemoglobin Concentration), which give insights into the size and concentration of hemoglobin in red blood cells.

Benefits of Using Testube EDTA

The benefits of using Testube EDTA are numerous, particularly in terms of preserving blood sample integrity and ensuring the accuracy of diagnostic results:

• Sample Integrity: By preventing the coagulation of blood, EDTA ensures that blood samples remain in their whole form, which is crucial for accurate hematological analysis.

• Preservation: EDTA is particularly effective at preserving the cellular components of blood, maintaining cell morphology, which is vital for differential white blood cell counts and red blood cell indices.

• Versatility: Testube EDTA is suitable for a variety of tests, including not only CBC but also additional specialized haematological investigations.

• Reliability: The use of high-quality EDTA in these test tubes ensures consistent and reliable results, which is critical for patient diagnoses and treatment plans.

Detailed Product Specifications

Physical Dimensions

Testube EDTA tubes are available in standard sizes commonly used in medical and laboratory practices. These include:

• Volume: Typically available in ranges from 1 mL to 10 mL, suitable for different types of blood sample requirements.
• Material: Made from high-grade plastic or glass, ensuring sterility and durability.

Sterility and Safety

• Sterilization: These tubes are pre-sterilized to prevent contamination of samples.
• Caps and Seals: The tubes come with tightly sealed, leak-proof caps, often color-coded (commonly lavender for EDTA tubes) for easy identification.
• Labels: Each tube is